Detalhe da pesquisa
1.
Discovery of new Schistosoma mansoni aspartyl protease inhibitors by structure-based virtual screening.
Mem Inst Oswaldo Cruz
; 118: e230031, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37672425
2.
Neurological impairment caused by Schistosoma mansoni systemic infection exhibits early features of idiopathic neurodegenerative disease.
J Biol Chem
; 297(2): 100979, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34303703
3.
COVID-19: molecular targets, drug repurposing and new avenues for drug discovery.
Mem Inst Oswaldo Cruz
; 115: e200254, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33027420
4.
N-acetyl-cysteine inhibits liver oxidative stress markers in BALB/c mice infected with Leishmania amazonensis.
Mem Inst Oswaldo Cruz
; 112(2): 146-154, 2017 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-28177049
5.
Increased tau phosphorylation and receptor for advanced glycation endproducts (RAGE) in the brain of mice infected with Leishmania amazonensis.
Brain Behav Immun
; 43: 37-45, 2015 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25014011
6.
Investigation into effects of antipsychotics on ectonucleotidase and adenosine deaminase in zebrafish brain.
Fish Physiol Biochem
; 41(6): 1383-92, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26156500
7.
Kinetics and molecular modeling studies on the inhibition mechanism of GH13 α-glycosidases by small molecule ligands.
Int J Biol Macromol
; 269(Pt 1): 132036, 2024 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38697429
8.
Kinetics studies on the inhibition mechanism of pancreatic α-amylase by glycoconjugated 1H-1,2,3-triazoles: a new class of inhibitors with hypoglycemiant activity.
Chembiochem
; 13(11): 1584-93, 2012 Jul 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-22753086
9.
Aluminum exposure alters behavioral parameters and increases acetylcholinesterase activity in zebrafish (Danio rerio) brain.
Cell Biol Toxicol
; 27(3): 199-205, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21240652
10.
Efficient identification of novel anti-glioma lead compounds by machine learning models.
Eur J Med Chem
; 189: 111981, 2020 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31978780
11.
Dealing with frequent hitters in drug discovery: a multidisciplinary view on the issue of filtering compounds on biological screenings.
Expert Opin Drug Discov
; 14(12): 1269-1282, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31416369
12.
Synthesis of new lophine-carbohydrate hybrids as cholinesterase inhibitors: cytotoxicity evaluation and molecular modeling.
Medchemcomm
; 10(12): 2089-2101, 2019 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32904099
13.
Ethanol and acetaldehyde alter NTPDase and 5'-nucleotidase from zebrafish brain membranes.
Neurochem Int
; 52(1-2): 290-6, 2008 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-17698255
14.
Ecto-nucleotidase pathway is altered by different treatments with fluoxetine and nortriptyline.
Eur J Pharmacol
; 583(1): 18-25, 2008 Mar 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-18280468
15.
Kinetic characterization of adenosine deaminase activity in zebrafish (Danio rerio) brain.
Comp Biochem Physiol B Biochem Mol Biol
; 151(1): 96-101, 2008 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-18582589
16.
Discovery of new Schistosoma mansoni aspartyl protease inhibitors by structure-based virtual screening
Mem. Inst. Oswaldo Cruz
; 118: e230031, 2023. tab, graf
Artigo
em Inglês
|
LILACS-Express
| ID: biblio-1506732
17.
Acute and subchronic copper treatments alter extracellular nucleotide hydrolysis in zebrafish brain membranes.
Toxicology
; 236(1-2): 132-9, 2007 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17499414
18.
Fluoxetine and nortriptyline affect NTPDase and 5'-nucleotidase activities in rat blood serum.
Life Sci
; 81(15): 1205-10, 2007 Sep 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-17889906
19.
Sertraline and clomipramine inhibit nucleotide catabolism in rat brain synaptosomes.
Toxicol In Vitro
; 21(4): 671-6, 2007 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-17317090
20.
Exposure to Hg2+ and Pb2+ changes NTPDase and ecto-5'-nucleotidase activities in central nervous system of zebrafish (Danio rerio).
Toxicology
; 226(2-3): 229-37, 2006 Sep 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-16930798